Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
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چکیده
منابع مشابه
Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland.
We have developed a mouse model of diet-induced obesity that shows numerous abnormalities relating to mammary gland function. Animals ate approximately 40% more calories when offered a high-fat diet and gained weight at three times the rate of controls. They exhibited reduced conception rates, increased peripartum pup mortality, and impaired lactogenesis. The impairment of lactogenesis involved...
متن کاملDiet-induced obesity impairs mammary development
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2005
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00433.2004